If you've spent much time in an emergency department or on a rig, you've seen how fast a patient given naloxone can go from zero breaths to fully awake, and sometimes straight into acute withdrawal.

When it comes to cardiac arrest, there's often confusion about whether CPR or defibrillation should come first. Current evidence shows that early defibrillation, combined with high-quality CPR, offers the best outcomes in most cases of ventricular fibrillation (VF). A brief period of CPR before defibrillation isn't necessary if a defibrillator is available.

Mixed drug overdoses can cause dangerous cardiac complications, including sodium channel blockade, a condition that disrupts the heart’s electrical conduction and can quickly lead to wide-complex arrhythmias, seizures, severe acidosis, and shock.

Mixed drug overdoses can cause dangerous cardiac complications, including sodium channel blockade, a condition that disrupts the heart’s electrical conduction and can quickly lead to wide-complex arrhythmias, seizures, severe acidosis, and shock.

Diltiazem (Cardizem) is a calcium channel blocker used to slow heart rate, most commonly in conditions like atrial fibrillation with rapid ventricular response (RVR) and other supraventricular tachycardias.